Barcelona have suffered a double injury blow ahead of key games in LaLiga and Champions League.
The Spanish champions will be without Raphinha and Joan García, as both players are both set for spells on the sidelines.
Raphinha will miss three weeks of action with a hamstring injury, while goalkeeper García will miss up to six weeks due to a meniscus problem in his knee.
The news comes after Gavi was ruled out for five months earlier this week at the same time as Fermín López picked up a muscle problem which will prevent him from playing for three weeks.
All four players will be out of action until at least after the international break.
This means they will miss the league game against Real Sociedad on Sunday and the Champions League group game with Paris Saint-Germain next Wednesday.
