At least four big Premier League clubs will not be in the draw for the FA Cup fifth-round ties on Monday night.
Arsenal, Liverpool, Chelsea, and Tottenham Hotspur have all been eliminated from the competition.
The Gunners were dumped out by Manchester United in the third round at the Emirates.
Bruno Fernandes opened the scoring for United, before Gabriel Magalhães levelled the game.
Martin Ødegaard missed the chance to win from the spot, while the Red Devils went on to book their spot via a penalty shoot-out.
Plymouth beat Liverpool 1-0 in the major upset of the FA Cup this season, thanks to a Hardie penalty.
Brighton came from behind to see off Chelsea 2-1 at the Amex.
Mathys Tel’s late goal was a mere consolation as Tottenham lost 2-1 to Aston Villa at Villa Park on Sunday.
For Spurs, they exited two domestic cups in one week, after getting drubbed 4-0 at Liverpool in the Carabao Cup semi-final second leg.